Experts report that there has been an "unprecedented increase" in measles cases in England and Wales.
Recent data from the Health Protection Agency showed there were 1,217 cases of measles from January to November 2008.
And 75% of the 115 cases diagnosed in November were outside the traditional hotspot of London - in the north west, west midlands and south east.
The HPA's Dr Mary Ramsay said the rise in cases was due to the "relatively low" MMR uptake over the past decade.
The HPA says too few children are receiving both doses of the combined measles, mumps and rubella jab.
Putting things in perspective, the number of measles cases in November 2008 was the same as was seen in the whole of 1996.
And even before numbers for December 2008 have been recorded, the figures show there were more measles cases last year than at any time in the last 12 years.
Earlier this week the UK was named as one of the worst countries in Europe for measles, with case levels dashing global hopes of eradicating the disease by 2010.
A Lancet study said that in 2006-7 most of the 12,000 cases in Europe were found in the UK and four other nations.
Dr Mary Ramsay, an immunisation expert at the HPA, said: "We are still experiencing an unprecedented increase in measles cases across the England and Wales.
"This continued rise is due to relatively low MMR vaccine uptake over the past decade and there are now a large number of children who are not fully protected with MMR.
"This means that measles, which is highly infectious, is spreading easily among these unvaccinated children."
She added: "The HPA is concerned that we may see measles epidemics take hold.
"We again are urging parents to get their children vaccinated. Although MMR coverage is starting to improve, we cannot stress enough that measles is serious and in some cases it can be fatal. Delaying immunisation puts children at risk."
Dr Ramsay said around eight out of 10 children were now receiving one dose of MMR by their second birthday.
But she added: "We shouldn't forget that the children who weren't vaccinated many years ago are at real risk."
In Scotland, the number of children receiving at least one dose of the MMR jab by the age of five has reached the target of 95% for the first time in December.
January 2009
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