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New IVF Womb Technique

New IVF Womb Technique

Could the womb produce better quality embryos than the test-tube?

An IVF technique which lets eggs develop in the womb rather than the test-tube straight after fertilisation is to be trialled in the UK. Researchers hope that the natural environment of the womb will help produce stronger embryos.

At the moment, an embryo is transferred to the womb after a few days growing in a laboratory. But this new method would see fertilised eggs placed in a device which is then planted in the womb. After a few days the device is taken out and the embryo deemed to have the best chances of survival reimplanted. The embryos produced this way are said to be of a higher quality and therefore have a better chance of survival.
 
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In addition to establishing whether the technique improves the chances of pregnancy, researchers are also keen to find out whether these embryos have fewer chromosomal abnormalities - which can lead to conditions such as Down's Syndrome. The group is currently recruiting 40 women under the age of 37 to take part in the trial, which will be carried out in Nottingham.

There is intense interest in developing new techniques which produce better quality embryos, and thus minimise the need for several embryos to be transferred to the womb in the hope that one will survive. This technique is producing large numbers of multiple births, which can put the lives of both mother and baby at risk.

Reproductive specialists are said to be cautious about the trial. Professor Adam Balen of the British Fertility Society said; "Even in natural conceptions the eggs do not spend those first days in the womb, but in the fallopian tubes. I'd like to see a bit more science before I got too excited about this."

Care Fertility says it hopes to have initial results by May or June, and a clearer picture of how successful the technique is by the end of year.

February 2008

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